DepartmentProf. Dept. of Pharmacy, College of Pharmacy / Professor
E-mailchulykim@hanyang.ac.kr
Office Phone031-400-5809
학과/직책약학대학 약학과 / 교수
이메일chulykim@hanyang.ac.kr
전화번호031-400-5809
Research Keywords
연구키워드
#생약학 연구실 - 생리활성천연물
Research Objectives
연구목표
Identification of Bio-active Compounds from Natural Products
Large-scale Purification of Natural Compounds
Natural Products with Skeletal Muscle Protective Activities
생리활성 천연물 성분의 분리 정제 구조 규명
천연물 성분의 대량 분리 정제
골격근 감소 개선 천연물 발굴 및 활성물질 규명
Brief Research Experience
주요경력
Seoul National University, Postdoc
KIST Gangneung Institute, Senior Researcher
Columbia University, Postdoc
Funding
National Research Foundation of Korea
BK21 Four Research Center
Ministry of Trade, Industry and Energy
Biopharmaceutical companies (Huons)
서울대학교 약학대학 박사후 연구원
한국과학기술연구원 강릉분원 선임연구원
미국 콜롬비아대학교, 박사후 연구원
수행과제 지원 기관
한국연구재단(과학기술정보통신부)
BK21 Four 사업단(교육부)
보건산업진흥원
바이오제약기업(휴온스 등)
Research Areas
연구분야
Isolation and Structural Elucidation of Natural Compounds
Discovery of Natural Molecules to Improve Skeletal Muscle Atrophy and Identification of Active Compounds
Identification of Nonenal, Aging Odor, Scavenging Natural Compounds
천연물 성분의 분리 정제 구조 규명
골격근 감소 천연물 소재의 발굴 및 활성 물질 규명
가령취 원인 물질인 노네날 제어 천연물 소재 개발
Thesis
논문
Kim, J. H., Jeon, J. S., Kim, J. H., Jung, E. J., Lee, Y. J., Gao, E. M., ... & Kim, C. Y. (2021). Bioassay-Guided Isolation of Two Eudesmane Sesquiterpenes from Lindera strychnifolia Using Centrifugal Partition Chromatography. Molecules, 26(17), 5269.
Kim, J. H., Jung, E. J., Lee, Y. J., Kim, C. Y., & Jeon, J. S. (2021). Application of Linear Gradient Solvent System in Centrifugal Partition Chromatography Facilitating Bioassay-Guided Fractionation of Yongdamsagan-Tang, Traditional Oriental Decoction. Evidence-Based Complementary and Alternative Medicine, 2021.
Park, C. L., Kim, J. H., Jeon, J. S., Lee, J. H., Zhang, K., Guo, S., ... & Kim, C. Y. (2022). Protective Effect of Alpinia oxyphylla Fruit against tert-Butyl Hydroperoxide-Induced Toxicity in HepG2 Cells via Nrf2 Activation and Free Radical Scavenging and Its Active Molecules. Antioxidants, 11(5), 1032.
Kim, H. M., Kim, J. Y., Kim, J. H., & Kim, C. Y. (2022). Kukoamine B from Lycii Radicis Cortex Protects Human Keratinocyte HaCaT Cells through Covalent Modification by Trans-2-Nonenal. Plants, 12(1), 163
Kim, J. Y., Kim, H. M., Kim, J. H., Lee, J. H., Zhang, K., Guo, S., ... & Kim, C. Y. (2022). Preventive effects of the butanol fraction of Justicia procumbens L. against dexamethasone-induced muscle atrophy in C2C12 myotubes. Heliyon, 8(11), e11597
Kim, J. Y., Kim, H. M., Kim, J. H., Guo, S., Lee, D. H., Lim, G. M., ... & Kim, C. Y. (2023). Salvia plebeia R. Br. and Rosmarinic Acid Attenuate Dexamethasone-Induced Muscle Atrophy in C2C12 Myotubes. International Journal of Molecular Sciences, 24(3), 1876.
Cooray, A., Chae, M. R., Wijerathne, T. D., Kim, D. G., Kim, J., Kim, C. Y., ... & Lee, K. P. (2023). Hexane fraction of Prunus japonica thunb. Seed extract enhances boar sperm motility via CatSper ion channel. Heliyon, 9(2).
Lee, Y., Kim, H. M., Kim, J. H., Lee, J. H., Zhang, K. X., Gao, E. M., ... & Kim, C. Y. (2022). Chemical constituents of the Ajuga multiflora bunge and their protective effects on dexamethasone-induced muscle atrophy in C2C12 myotubes. Natural Product Research, 1-8.